The eSPC platform provides easy to use software for the understanding of biophysical experiments.
Estimating binding affinities by isothermal analysis. Analyse protein-ligand titration curves, fit fluorescence curves, calculate KDs.
Assessing protein stability under different conditions. Calculate Tm, Tonset, DH.
Estimating binding affinities by thermophoresis shift or initial fluorescence analysis.
Estimating molecular masses in a sample.
Estimating sample homogeneity and hydrodynamic radius.
Analysing biomolecules conformation. Perform spectra decomposition, estimate unfolding parameters, or calculate secondary structure content
Assessing binding kinetics. Perform global fitting of association and dissociation curves, estimate binding rates.
eSPC, a tool for analysing protein biophysics
EMBL (c/o DESY), Notkestrasse 85, Build. 25a, 22607 Hamburg, Germany
Tel: +49 40 89 902-110 or 111